BDBM50427620 CHEMBL2323507::US9346803, 2

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(CCC(O)=O)c(C)c2c1

InChI Key InChIKey=NDOLIIHMVOZCMD-UHFFFAOYSA-N

Data  9 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50427620   

TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50427620(CHEMBL2323507 | US9346803, 2)
Affinity DataIC50:  14.5nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50427620(CHEMBL2323507 | US9346803, 2)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of human recombinant AKR1C2-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed